Hypothalamic Obesity in Craniopharyngioma Patients: Disturbed Energy Homeostasis Related to Extent of Hypothalamic Damage and Its Implication for Obesity Intervention

Hypothalamic Obesity in Craniopharyngioma Patients: Disturbed Energy Homeostasis Related to Extent of Hypothalamic Damage and Its Implication for Obesity Intervention

Hypothalamic obesity (HO) occurs in patients with tumors and lesions in the medial hypothalamic region. Hypothalamic dysfunction can lead to hyperinsulinemia and leptin resistance. This review is focused on HO caused by craniopharyngiomas (CP), which are the most common childhood brain tumors of non...

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Bibliographic Details
Main Author: Christian L. Roth
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Journal of Clinical Medicine
Subjects:
hypothalamic obesity
craniopharyngioma
risk factors
neuroimaging
rodent models
inflammation
pharmacological interventions
Online Access:http://www.mdpi.com/2077-0383/4/9/1774

Internet

http://www.mdpi.com/2077-0383/4/9/1774

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