Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells

Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells

Abstract Background Costunolide, a sesquiterpene lactone extracted from Radix Aucklandiae, has the activity against multiple cancers. However, the effect of costunolide on gastric cancer (GC) have remained to be ambiguous. In this study, we investigated the underlying mechanisms of apoptosis induced...

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Bibliographic Details
Main Authors: Zhanpeng Yan, Tingting Xu, Zhentao An, Ying Hu, Wanzhen Chen, Jinxia Ma, Changle Shao, Fangshi Zhu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Costunolide
Apoptosis
Gastric cancer
Xenografted nude mice
Online Access:http://link.springer.com/article/10.1186/s12906-019-2569-6

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http://link.springer.com/article/10.1186/s12906-019-2569-6

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