Regulation of Pax7 protein levels by caspase-3 and proteasome activity in differentiating myoblasts
The transcription factor Pax7 negatively regulates the activity of the muscle regulatory transcription factor MyoD, preventing muscle precursor cells from undergoing terminal differentiation. In this context, the ratio between Pax7 and MyoD protein levels is thought to be critical in allowing myogen...
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| Format: | Article |
| Language: | English |
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BMC
2011-01-01
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| Series: | Biological Research |
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| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000400002 |