An N-Linked Bidentate Phosphoramidite Ligand (N-Me-BIPAM) for Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Ketones

An N-Linked Bidentate Phosphoramidite Ligand (N-Me-BIPAM) for Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Ketones

A new bidentate phosphoramidite (N-Me-BIPAM) based on Shibasaki’s N-linked BINOL was synthesized. This ligand appears to be highly effective for rhodium-catalyzed asymmetric conjugated addition of arylboronic acids to α,β-unsaturated enones. The reaction of or...

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Bibliographic Details
Main Authors: Norio Miyaura, Yoshinori Takahashi, Kazunori Kurihara, Yasunori Yamamoto
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
asymmetric conjugate addition
rhodium catalyst
bidentate phosphoramidite ligand
Online Access:http://www.mdpi.com/1420-3049/18/1/14

Internet

http://www.mdpi.com/1420-3049/18/1/14

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