Additive Effects of the Risk Alleles of PNPLA3 and TM6SF2 on Nonalcoholic Fatty Liver Disease (NAFLD) in a Chinese Population

Additive Effects of the Risk Alleles of PNPLA3 and TM6SF2 on Nonalcoholic Fatty Liver Disease (NAFLD) in a Chinese Population

Recent genome-wide association studies (GWASs) identified that variants in or near PNPLA3, NCAN, GCKR, LYPLAL1, TM6SF2 were significantly associated with nonalcoholic fatty liver disease (NAFLD) in multiple ethnic groups. Studies on their impact on NAFLD in Han Chinese is still limited. In this stud...

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Bibliographic Details
Main Authors: Xiaoliang Wang, Zhipeng Liu, Kai Wang, Zhaowen Wang, Xing Sun, Lin Zhong, Guilong Deng, Guohe Song, Baining Sun, Zhihai Peng, Wanqing Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Genetics
Subjects:
Chinese
NAFLD
Additive effects
PNPLA3
TM6SF2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00140/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00140/full

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