Atopic dermatitis: immune deviation, barrier dysfunction, IgE autoreactivity and new therapies

Atopic dermatitis: immune deviation, barrier dysfunction, IgE autoreactivity and new therapies

Atopic dermatitis (AD) is a chronic or chronically relapsing, eczematous, severely pruritic skin disorder mostly associated with IgE elevation and skin barrier dysfunction due to decreased filaggrin expression. The lesional skin of AD exhibits Th2- and Th22-deviated immune reactions that are progres...

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Bibliographic Details
Main Authors: Masutaka Furue, Takahito Chiba, Gaku Tsuji, Dugarmaa Ulzii, Makiko Kido-Nakahara, Takeshi Nakahara, Takafumi Kadono
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Allergology International
Subjects:
Atopic dermatitis
Filaggrin
IgE autoreactivity
Th2
Th22
Online Access:http://www.sciencedirect.com/science/article/pii/S132389301630171X

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http://www.sciencedirect.com/science/article/pii/S132389301630171X

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