Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models

Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models

Group A Streptococcus (GAS) is an important human pathogen responsible for both superficial infections and invasive diseases. Autoimmune sequelae may occur upon repeated infection. For this reason, development of a vaccine against GAS represents a major challenge, since certain GAS components may tr...

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Bibliographic Details
Main Authors: Tania Rivera-Hernandez, Manisha Pandey, Anna Henningham, Jason Cole, Biswa Choudhury, Amanda J. Cork, Christine M. Gillen, Khairunnisa Abdul Ghaffar, Nicholas P. West, Guido Silvestri, Michael F. Good, Peter M. Moyle, Istvan Toth, Victor Nizet, Michael R. Batzloff, Mark J. Walker
Format: Article
Language:English
Published: American Society for Microbiology 2016-06-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/3/e00618-16

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http://mbio.asm.org/cgi/content/full/7/3/e00618-16

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