MicroRNA-665 mediates propofol-induced cell apoptosis in human stem cell-derived neurons

We aimed to evaluate the neurotoxicity and mechanisms of anesthetics propofol in hESC-derived neurons. Cell apoptosis in hESC-derived neurons' exposure to 4, 10 and 20 μg/mL propofol for 6 h was assessed using terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate in situ nick...

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Bibliographic Details
Main Authors: Lili Jiang, Fengyun Yang, Qin Zhao, Lixiao Pan
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Bioengineered
Subjects:
Online Access:http://dx.doi.org/10.1080/21655979.2019.1682105