Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma.

Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma.

<h4>Background</h4>Temozolomide (TMZ) has been the standard-of-care chemotherapy for glioblastoma (GBM) patients for more than a decade. Despite this long time in use, significant questions remain regarding how best to optimize TMZ therapy for individual patients. Understanding the relat...

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Bibliographic Details
Main Authors: Susan Christine Massey, Haylye White, Paula Whitmire, Tatum Doyle, Sandra K Johnston, Kyle W Singleton, Pamela R Jackson, Andrea Hawkins-Daarud, Bernard R Bendok, Alyx B Porter, Sujay Vora, Jann N Sarkaria, Leland S Hu, Maciej M Mrugala, Kristin R Swanson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230492

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https://doi.org/10.1371/journal.pone.0230492

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