Pepsin promotes IL-8 signaling-induced epithelial–mesenchymal transition in laryngeal carcinoma
Abstract Background Laryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting considerable attention. In recent years, the causal role between LPR and laryngeal carcinoma has been debated. The main harmful component of LPR is pepsin, which has been shown to induce mucosal inflamma...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-03-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12935-019-0772-7 |