The ratios of estradiol and progesterone to testosterone influence the severity of facioscapulohumeral muscular dystrophy

The ratios of estradiol and progesterone to testosterone influence the severity of facioscapulohumeral muscular dystrophy

Background: Facioscapulohumeral muscular dystrophy (FSHD) occurs as a consequence of genetic deletion of D4Z4 repeats on chromosome 4q35. Onset of FSHD is earlier in males, suggesting that testosterone may trigger the disease. In accordance, the rapid progression of disease in women after menopause...

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Bibliographic Details
Main Authors: Ceren Hangul, Selen Bozkurt, Ugur Bilge, Sebahat Ozdem, Hasan Altunbas, Hilmi Uysal, Filiz Koc, Sibel Berker Karauzum
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neurological Sciences and Neurophysiology
Subjects:
estradiol
facioscapulohumeral muscular dystrophy
fshd
progesterone
testosterone
Online Access:http://www.nsnjournal.org/article.asp?issn=2636-865X;year=2020;volume=37;issue=4;spage=190;epage=196;aulast=Hangul

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http://www.nsnjournal.org/article.asp?issn=2636-865X;year=2020;volume=37;issue=4;spage=190;epage=196;aulast=Hangul

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