Analysis of AMB-FUBINACA Biotransformation Pathways in Human Liver Microsome and Zebrafish Systems by Liquid Chromatography-High Resolution Mass Spectrometry

Analysis of AMB-FUBINACA Biotransformation Pathways in Human Liver Microsome and Zebrafish Systems by Liquid Chromatography-High Resolution Mass Spectrometry

In this study, the metabolic profiles of a new illicit drug AMB-FUBINACA were investigated using both human liver microsome and zebrafish models. Liquid chromatography Q Extractive HF Hybrid Quadrupole-Orbitrap mass spectrometry (LC-QE-HF-MS) was employed to analyze the metabolic sites and pathways....

Full description

Bibliographic Details
Main Authors: Duo-qi Xu, Wen-fang Zhang, Jing Li, Ji-fen Wang, Shi-yang Qin, Jiang-hai Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Chemistry
Subjects:
AMB-FUBINACA
synthetic cannabinoids
HR-MS
human liver microsome
metabolism
zebrafish
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00240/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2019.00240/full

Similar Items