Profiling of Human Neural Crest Chemoattractant Activity as a Replacement of Fetal Bovine Serum for In Vitro Chemotaxis Assays

Profiling of Human Neural Crest Chemoattractant Activity as a Replacement of Fetal Bovine Serum for In Vitro Chemotaxis Assays

Fetal bovine serum (FBS) is the only known stimulus for the migration of human neural crest cells (NCCs). Non-animal chemoattractants are desirable for the optimization of chemotaxis as-says to be incorporated in a test battery for reproductive and developmental toxicity. We con-firmed here in an op...

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Bibliographic Details
Main Authors: Xenia Dolde, Christiaan Karreman, Marianne Wiechers, Stefan Schildknecht, Marcel Leist
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
neural crest cells
cell migration
chemotaxis
fetal bovine serum
human platelet lysate
Online Access:https://www.mdpi.com/1422-0067/22/18/10079

Internet

https://www.mdpi.com/1422-0067/22/18/10079

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