Synthetic carbohydrate-based vaccines: challenges and opportunities

Abstract Glycoconjugate vaccines based on bacterial capsular polysaccharides (CPS) have been extremely successful in preventing bacterial infections. The glycan antigens for the preparation of CPS based glycoconjugate vaccines are mainly obtained from bacterial fermentation, the quality and length o...

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Bibliographic Details
Main Authors: Ravinder Mettu, Chiang-Yun Chen, Chung-Yi Wu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Biomedical Science
Subjects:
Online Access:https://doi.org/10.1186/s12929-019-0591-0