Fast lightweight accurate xenograft sorting
Abstract Motivation With an increasing number of patient-derived xenograft (PDX) models being created and subsequently sequenced to study tumor heterogeneity and to guide therapy decisions, there is a similarly increasing need for methods to separate reads originating from the graft (human) tumor an...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-04-01
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| Series: | Algorithms for Molecular Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13015-021-00181-w |