Anatomically and functionally distinct locus coeruleus efferents mediate opposing effects on anxiety-like behavior

The locus coeruleus (LC) is a critical node in the stress response, and its activation has been shown to promote hypervigilance and anxiety-like behavior. This noradrenergic nucleus has historically been considered homogeneous with highly divergent neurons that operate en masse to collectively affec...

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Bibliographic Details
Main Authors: Olga Borodovitsyna, Brenna C. Duffy, Anthony E. Pickering, Daniel J. Chandler
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Neurobiology of Stress
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289520300746