The experimental model of transition from compensated cardiac hypertrophy to failure created by transverse aortic constriction in mice

The experimental model of transition from compensated cardiac hypertrophy to failure created by transverse aortic constriction in mice

Background: Transverse aortic constriction (TAC) operation is used as an experimental model of left ventricular (LV) hypertrophy and LV failure in mice. The severity of LV remodeling or failure may depend on the degree of TAC, but is variable among operated animals. Therefore, we tried to identify t...

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Bibliographic Details
Main Authors: Takaaki Furihata, Shintaro Kinugawa, Shingo Takada, Arata Fukushima, Masashige Takahashi, Tsuneaki Homma, Yoshihiro Masaki, Masaya Tsuda, Junichi Matsumoto, Wataru Mizushima, Shouji Matsushima, Takashi Yokota, Hiroyuki Tsutsui
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:International Journal of Cardiology: Heart & Vasculature
Subjects:
Methodology
Transverse aortic constriction
Cardiac hypertrophy
Cardiac failure
Mice
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906716300112

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http://www.sciencedirect.com/science/article/pii/S2352906716300112

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