Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

The OX40-OX40L axis is a crucial component of the costimulatory requirement of CD4 T cell responses. Here, the authors show context and cell type specific expression of OX40L for driving Th1 cell generation during acute and chronic models of infection.

Bibliographic Details
Main Authors: Dominika W. Gajdasik, Fabrina Gaspal, Emily E. Halford, Remi Fiancette, Emma E. Dutton, Claire Willis, Timo Rückert, Chiara Romagnani, Audrey Gerard, Sarah L. Bevington, Andrew S. MacDonald, Marina Botto, Timothy Vyse, David R. Withers
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17293-3

Internet

https://doi.org/10.1038/s41467-020-17293-3

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