Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in l-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT1R Expression

Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in l-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT1R Expression

This study examined the effect of Carthamus tinctorius (CT) extract plus captopril treatment on blood pressure, vascular function, nitric oxide (NO) bioavailability, oxidative stress and renin-angiotensin system (RAS) in Nω-Nitro-l-arginine methyl ester (l-NAME)-induced hypertension. Rats were treat...

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Bibliographic Details
Main Authors: Putcharawipa Maneesai, Patoomporn Prasarttong, Sarawoot Bunbupha, Upa Kukongviriyapan, Veerapol Kukongviriyapan, Panot Tangsucharit, Parichat Prachaney, Poungrat Pakdeechote
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Nutrients
Subjects:
Carthamus tinctorius L.
captopril
">l-NAME-induced hypertension
renin-angiotensin system
eNOS expression
oxidative stress
Online Access:http://www.mdpi.com/2072-6643/8/3/122

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http://www.mdpi.com/2072-6643/8/3/122

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