Mutational analysis of circulating tumor cells from colorectal cancer patients and correlation with primary tumor tissue.

Circulating tumor cells (CTCs) provide a non-invasive accessible source of tumor material from patients with cancer. The cellular heterogeneity within CTC populations is of great clinical importance regarding the increasing number of adjuvant treatment options for patients with metastatic carcinomas...

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Main Authors: Anna Lyberopoulou, Gerasimos Aravantinos, Efstathios P Efstathopoulos, Nikolaos Nikiteas, Penelope Bouziotis, Athina Isaakidou, Apostolos Papalois, Evangelos Marinos, Maria Gazouli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4406761?pdf=render