Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres.
The catalytic subunit of yeast telomerase, Est2p, is a telomere associated throughout most of the cell cycle, while the Est1p subunit binds only in late S/G2 phase, the time of telomerase action. Est2p binding in G1/early S phase requires a specific interaction between telomerase RNA (TLC1) and Ku80...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-10-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2567097?pdf=render |