Structural studies of P-type ATPase–ligand complexes using an X-ray free-electron laser

Structural studies of P-type ATPase–ligand complexes using an X-ray free-electron laser

Membrane proteins are key players in biological systems, mediating signalling events and the specific transport of e.g. ions and metabolites. Consequently, membrane proteins are targeted by a large number of currently approved drugs. Understanding their functions and molecular mechanisms is greatly...

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Bibliographic Details
Main Authors: Maike Bublitz, Karol Nass, Nikolaj D. Drachmann, Anders J. Markvardsen, Matthias J. Gutmann, Thomas R. M. Barends, Daniel Mattle, Robert L. Shoeman, R. Bruce Doak, Sébastien Boutet, Marc Messerschmidt, Marvin M. Seibert, Garth J. Williams, Lutz Foucar, Linda Reinhard, Oleg Sitsel, Jonas L. Gregersen, Johannes D. Clausen, Thomas Boesen, Kamil Gotfryd, Kai-Tuo Wang, Claus Olesen, Jesper V. Møller, Poul Nissen, Ilme Schlichting
Format: Article
Language:English
Published: International Union of Crystallography 2015-07-01
Series:IUCrJ
Subjects:
XFEL
P-type ATPases
ligand screening
serial femtosecond crystallography
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252515008969

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http://scripts.iucr.org/cgi-bin/paper?S2052252515008969

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