Boolean Feedforward Neural Network Modeling of Molecular Regulatory Networks for Cellular State Conversion

The molecular regulatory network (MRN) within a cell determines cellular states and transitions between them. Thus, modeling of MRNs is crucial, but this usually requires extensive analysis of time-series measurements, which is extremely difficult to obtain from biological experiments. However, sing...

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Bibliographic Details
Main Authors: Sang-Mok Choo, Laith M. Almomani, Kwang-Hyun Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.594151/full