Monitoring the hydrolyzation of aspirin during the dissolution testing for aspirin delayed-release tablets with a fiber-optic dissolution system

The purpose of this study was to investigate the hydrolyzation of aspirin during the process of dissolution testing for aspirin delayed-release tablets. Hydrolysis product of salicylic acid can result in adverse effects and affect the determination of dissolution rate assaying. In this study, the te...

Full description

Bibliographic Details
Main Authors: Yan Wang, Ping-Ping Xu, Xin-Xia Li, Kun Nie, Ming-Fu Tuo, Bin Kong, Jian Chen
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177912000810