Improving predictive models for Alzheimer's disease using GWAS data by incorporating misclassified samples modeling.

Late-onset Alzheimer's Disease (LOAD) is the most common form of dementia in the elderly. Genome-wide association studies (GWAS) for LOAD have open new avenues to identify genetic causes and to provide diagnostic tools for early detection. Although several predictive models have been proposed u...

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Bibliographic Details
Main Authors: Brissa-Lizbeth Romero-Rosales, Jose-Gerardo Tamez-Pena, Humberto Nicolini, Maria-Guadalupe Moreno-Treviño, Victor Trevino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232103