RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson's disease

RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson's disease

Regulators of G-protein signalling (RGS) proteins are implicated in striatal G-protein coupled receptor (GPCR) sensitisation in the pathophysiology of l-DOPA-induced abnormal involuntary movements (AIMs), also known as dyskinesia (LID), in Parkinson's disease (PD). In this study, we investigate...

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Bibliographic Details
Main Authors: Wai Kin D. Ko, Marie-Laure Martin-Negrier, Erwan Bezard, Alan R. Crossman, Paula Ravenscroft
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Neurobiology of Disease
Subjects:
RGS4
Parkinson's disease
l-DOPA-induced dyskinesia
Abnormal involuntary movements
Antisense oligonucleotides
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114001776

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http://www.sciencedirect.com/science/article/pii/S0969996114001776

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