Adjuvantic cytokine IL-33 improves the protective immunity of cocktailed DNA vaccine of ROP5 and ROP18 against toxoplasma gondii infection in mice

Toxoplasma gondii is a threat for immunocompromized individuals, and no treatment is available for enhancing immunity against infection. Molecular adjuvants may improve the efficacy of DNA vaccine-induced T cell immunity. Here, we report that cocktailed DNA immunization with ROP5 and ROP18 boosted i...

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Bibliographic Details
Main Authors: Zhu Yu-Chao, He Yong, Liu Jian-Fa, Chen Jia
Format: Article
Language:English
Published: EDP Sciences 2020-01-01
Series:Parasite
Subjects:
Online Access:https://www.parasite-journal.org/articles/parasite/full_html/2020/01/parasite190121/parasite190121.html