Rapid and Sensitive Detection of Breast Cancer Cells in Patient Blood with Nuclease-Activated Probe Technology

A challenge for circulating tumor cell (CTC)-based diagnostics is the development of simple and inexpensive methods that reliably detect the diverse cells that make up CTCs. CTC-derived nucleases are one category of proteins that could be exploited to meet this challenge. Advantages of nucleases as...

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Bibliographic Details
Main Authors: Sven Kruspe, David D. Dickey, Kevin T. Urak, Giselle N. Blanco, Matthew J. Miller, Karen C. Clark, Elliot Burghardt, Wade R. Gutierrez, Sneha D. Phadke, Sukriti Kamboj, Timothy Ginader, Brian J. Smith, Sarah K. Grimm, James Schappet, Howard Ozer, Alexandra Thomas, James O. McNamara, II, Carlos H. Chan, Paloma H. Giangrande
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117302305