A dynamic real time in vivo and static ex vivo analysis of granulomonocytic cell migration in the collagen-induced arthritis model.

Neutrophilic granulocytes and monocytes (granulomonocytic cells; GMC) drive the inflammatory process at the earliest stages of rheumatoid arthritis (RA). The migratory behavior and functional properties of GMC within the synovial tissue are, however, only incompletely characterized. Here we have ana...

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Bibliographic Details
Main Authors: Ruth Byrne, Eva Rath, Anastasiya Hladik, Birgit Niederreiter, Michael Bonelli, Sophie Frantal, Josef S Smolen, Clemens Scheinecker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329447?pdf=render