Impact of serum albumin levels on supratherapeutic PT-INR control and bleeding risk in atrial fibrillation patients on warfarin: A prospective cohort study

Background: Since warfarin is primarily bound to serum albumin, hypoalbuminemia is likely to increase the free fraction of warfarin and to increase the risk of bleeding. We prospectively evaluated the impact of serum albumin levels (ALB) on international normalized ratio of prothrombin time (PT-INR)...

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Bibliographic Details
Main Authors: Mayumi Kawai, Masahide Harada, Yuji Motoike, Masayuki Koshikawa, Tomohide Ichikawa, Eiichi Watanabe, Yukio Ozaki
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:International Journal of Cardiology: Heart & Vasculature
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906718301684