Aberrant expression of histone deacetylases 4 in cognitive disorders: molecular mechanisms and a potential target

Histone acetylation is a major mechanism of chromatin remodeling, contributing to epigenetic regulation of gene transcription. Histone deacetylases (HDACs) are involved in both physiological and pathological conditions by regulating the status of histone acetylation. Although histone deacetylase 4 (...

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Bibliographic Details
Main Authors: Yili Wu, fei hou, xin wang, qingsheng kong, xiaolin han, bo bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00114/full