The bone microenvironment promotes tumor growth and tissue perfusion compared with striated muscle in a preclinical model of prostate cancer in vivo

The bone microenvironment promotes tumor growth and tissue perfusion compared with striated muscle in a preclinical model of prostate cancer in vivo

Abstract Background Prostate cancer-related morbidity is associated with its preferential spread to the bone. Although the molecular interactions between the bone microenvironment and cancer cells have been researched extensively, the relevance of the microvascular properties of prostate cancer bone...

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Bibliographic Details
Main Authors: Haider Mussawy, Lennart Viezens, Malte Schroeder, Svenja Hettenhausen, Jördis Sündermann, Jasmin Wellbrock, Kai Kossow, Christian Schaefer
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
Bone microenvironment
Femur window
Dorsal skinfold chamber
Tumor growth
Prostate cancer
Intravital microscopy
Online Access:http://link.springer.com/article/10.1186/s12885-018-4905-5

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http://link.springer.com/article/10.1186/s12885-018-4905-5

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