Simultaneous determination of ethinyl estradiol and drospirenone in oral contraceptive by high performance liquid chromatography

Simultaneous determination of ethinyl estradiol and drospirenone in oral contraceptive by high performance liquid chromatography

A simple, rapid, economical and reliable high performance liquid chromatographic method has been developed and successfully applied in simultaneous determination of ethinyl estradiol and drospirenone in coated tablets. The HPLC method was performed on a LiChroCART® 100RP column (125x4 mm i.d., 5 µm)...

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Bibliographic Details
Main Authors: Viviane Benevenuti Silva, Angel Arturo Gaona Galdos, Cintia Maria Alves Mothe, Michele Bacchi Pallastrelli, Maria Segunda Aurora Prado, Anil Kumar Singh, Erika Rosa Maria Kedor-Hackmann, Maria Inês Rocha Miritello Santoro
Format: Article
Language:English
Published: Universidade de São Paulo 2013-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Comprimidos revestidos
Cromatografia líquida de alta eficiência
Etinilestradiol
Drospirenona
Detecção por fluorescência
Detecção no UV
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300013&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300013&lng=en&tlng=en

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