Small molecule inhibitors of cyclin-dependent kinase 9 for cancer therapy
Cyclin-dependent kinase 9 (CDK9) plays a vital role in transcription through regulation of short-lived anti-apoptotic genes required for cancer cell survival. Therefore, targeting CDK9 with small molecule inhibitors has emerged as a potential cancer therapy. This article reviews the most recent CDK9...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2021-01-01
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Series: | Journal of Enzyme Inhibition and Medicinal Chemistry |
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Online Access: | http://dx.doi.org/10.1080/14756366.2021.1890726 |