Effects of In Vivo Gluten Challenge on PBMC Gene Expression Profiles in Diet Treated Celiac Disease

Effects of In Vivo Gluten Challenge on PBMC Gene Expression Profiles in Diet Treated Celiac Disease

The pathological mechanisms that lead to the onset and reactivation of celiac disease (CD) remain largely unknown. While gluten free diet (GFD) improves the intestinal damage and associated clinical symptoms in majority of cases, it falls short of providing full recovery. Additionally, late or misdi...

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Bibliographic Details
Main Authors: Dawit A. Yohannes, Andrea de Kauwe, Katri Kaukinen, Kalle Kurppa, Markku Mäki, Robert P. Anderson, Sten Linnarsson, Dario Greco, Päivi Saavalainen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
celiac disease
celiac disease gene expression analysis
celiac disease RNA sequencing
celiac disease transcriptomics
pathway analysis, gluten challenge
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.594243/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.594243/full

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