Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring

Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring

There is now strong evidence that the paternal contribution to offspring phenotype at fertilisation is more than just DNA. However, the identity and mechanisms of this nongenetic inheritance are poorly understood. One of the more important questions in this research area is: do changes in sperm DNA...

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Bibliographic Details
Main Authors: Neil A Youngson, Virginie Lecomte, Christopher A Maloney, Preston Leung, Jia Liu, Luke B Hesson, Fabio Luciani, Lutz Krause, Margaret J Morris
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Asian Journal of Andrology
Subjects:
methylation; obesity; spermatozoa
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2016;volume=18;issue=6;spage=930;epage=936;aulast=Youngson

Internet

http://www.ajandrology.com/article.asp?issn=1008-682X;year=2016;volume=18;issue=6;spage=930;epage=936;aulast=Youngson

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