Simple Mathematical Models Do Not Accurately Predict Early SIV Dynamics

Simple Mathematical Models Do Not Accurately Predict Early SIV Dynamics

Upon infection of a new host, human immunodeficiency virus (HIV) replicates in the mucosal tissues and is generally undetectable in circulation for 1–2 weeks post-infection. Several interventions against HIV including vaccines and antiretroviral prophylaxis target virus replication at this earliest...

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Bibliographic Details
Main Authors: Cecilia Noecker, Krista Schaefer, Kelly Zaccheo, Yiding Yang, Judy Day, Vitaly V. Ganusov
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Viruses
Subjects:
early SIV/HIV infection
mathematical model
eclipse phase
stochastic
Gillespie algorithm
Online Access:http://www.mdpi.com/1999-4915/7/3/1189

Internet

http://www.mdpi.com/1999-4915/7/3/1189

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