Deciphering the Astrocyte Reaction in Alzheimer’s Disease

Reactive astrocytes were identified as a component of senile amyloid plaques in the cortex of Alzheimer’s disease (AD) patients several decades ago. However, their role in AD pathophysiology has remained elusive ever since, in part owing to the extrapolation of the literature from primary astrocyte...

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Bibliographic Details
Main Authors: Beatriz G. Perez-Nievas, Alberto Serrano-Pozo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00114/full