Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism
The most commonly mutated gene in all human cancers is the tumor suppressor gene <i>TP53</i>; however, in addition to the loss of tumor suppressor functions, mutations in <i>TP53</i> can also promote cancer progression by altering cellular iron acquisition and metabolism. The...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
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Series: | Nutrients |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6643/11/9/2144 |