Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism

The most commonly mutated gene in all human cancers is the tumor suppressor gene <i>TP53</i>; however, in addition to the loss of tumor suppressor functions, mutations in <i>TP53</i> can also promote cancer progression by altering cellular iron acquisition and metabolism. The...

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Bibliographic Details
Main Authors: Stephen L. Clarke, Laurie R. Thompson, Eshan Dandekar, Aishwarya Srinivasan, McKale R. Montgomery
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/9/2144