Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans

Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans

Ebola virus disease (EVD) is associated with elevated cytokine levels, and hypercytokinemia is more pronounced in fatal cases. This type of hyperinflammatory state is reminiscent of 2 rheumatologic disorders known as macrophage activation syndrome and hemophagocytic lymphohistiocytosis, which are ch...

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Bibliographic Details
Main Authors: Anita K. McElroy, Punya Shrivastava-Ranjan, Jessica R. Harmon, Roosecelis B. Martines, Luciana Silva-Flannery, Timothy D. Flietstra, Colleen S. Kraft, Aneesh K. Mehta, G. Marshall Lyon, Jay B. Varkey, Bruce S. Ribner, Stuart T. Nichol, Sherif R. Zaki, Christina F. Spiropoulou
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2019-02-01
Series:Emerging Infectious Diseases
Subjects:
Ebola
inflammation
macrophage
MAS
HLH
Ebola virus
Online Access:https://wwwnc.cdc.gov/eid/article/25/2/18-1326_article

Internet

https://wwwnc.cdc.gov/eid/article/25/2/18-1326_article

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