In Situ Liver Expression of HBsAg/CD3-Bispecific Antibodies for HBV Immunotherapy

In Situ Liver Expression of HBsAg/CD3-Bispecific Antibodies for HBV Immunotherapy

Current therapies against hepatitis B virus (HBV) do not reliably cure chronic infection, necessitating new therapeutic approaches. The T cell response can clear HBV during acute infection, and the adoptive transfer of antiviral T cells during bone marrow transplantation can cure patients of chronic...

Full description

Bibliographic Details
Main Authors:	Robert L. Kruse, Thomas Shum, Xavier Legras, Mercedes Barzi, Frank P. Pankowicz, Stephen Gottschalk, Karl-Dimiter Bissig
Format:	Article
Language:	English
Published:	Elsevier 2017-12-01
Series:	Molecular Therapy: Methods & Clinical Development
Subjects:	hepatitis B virus viral hepatitis bispecific antibody T cell gene therapy immunotherapy liver
Online Access:	http://www.sciencedirect.com/science/article/pii/S2329050117300955

Similar Items

HBV感染者HBsAg和抗-HBs双阳性发生机制
by: REN Meixin
Published: (2014-04-01)

Clinical features of HBsAg-negative HBV-related hepatocellular carcinoma
by: MA Yan, et al.
Published: (2017-04-01)

HBsAg loss with HBsAg/anti-HBs seroconversion and non-detectable HCV-RNA in a patient with chronic HBV e-minus/HCV hepatitis treated with two cycles of antiviral therapy
by: Antonio Salvio, et al.
Published: (2012-01-01)

PROPORTION OF HBsAg AND HBeAg POSITIVE IN MATERNAL PATIENTS AND THEIR HBsAg POSITIVES BABIES WITH IMMUNOPROPHYLAXIS OF HBV IMMUNIZATION IN Dr. SOETOMO GENERAL HOSPITAL, SURABAYA
by: Melina Rosita Tanadi, et al.
Published: (2017-08-01)

The prevalence of HBsAg and Anti-HCV in pregnant women in Adıyaman
by: Servet Kölgelier, et al.
Published: (2009-01-01)

Is Quantitative HBsAg Measurement a Reliable Substitute for HBV DNA Quantitation?
by: Mohammad Reza Mahdavi, et al.
Published: (2015-07-01)

HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers
by: Adnan S. Wiharta, et al.
Published: (2018-11-01)

Using the Quantitative Determination of HBsAg to Monitor the Natural History of Chronic HBV-Infection
by: I.A. Zaitsev
Published: (2015-09-01)

IL-10 Promoter Polymorphism Distribution among HBsAg-Reactive and HBsAg-Nonreactive Blood Donors
by: Rahmat Azhari Kemal, et al.
Published: (2020-03-01)

Comparative analysis of the safety and efficacy of HBsAg-1018 versus HBsAg-Eng: a meta-analysis
by: Lin Zhang, et al.
Published: (2020-01-01)

LDH-isoenzymes and HBsAg.
by: Bharucha Z, et al.
Published: (1980-04-01)

Factors related to duration of serum HBsAg in patients with acute hepatitis B
by: ZHANG Jiawei
Published: (2014-11-01)

Change of HBsAg Screening and Seropositivity in Pregnant Women By the Years
by: Gökhan TOSUN, et al.
Published: (2019-12-01)

Change in HBsAg quantification after HBV DNA negative conversion in chronic hepatitis B patients treated with nucleos(t)ide analogues
by: ZHOU Youqian, et al.
Published: (2019-05-01)

Seroprevalence of HBsAg, Anti-HBs, anti-HDV and HDVAg in Inonu University Medical Faculty Hospital, 2012 [Inonu Universitesi Tip Fakultesi Hastanesinde, 2012 Yilinda, HBsAg, Anti-HBs, Anti-HDV ve HDVAg Seroprevalansi]
by: Yucel Duman, et al.
Published: (2014-03-01)

Suppressive effect on the secretion of hepatitis B surface antigen (HBsAg) by Phyllanthus urinaria in alexander cells.
Published: (2003)

Clinical characteristics of patients with HBsAg(+) versus HBsAg(-)/HBcAb(+) primary hepatic carcinoma treated by hepatectomy: a comparative analysis
by: YANG Keli
Published: (2015-06-01)

Auxiliary Liver Graft Can Be Protected From HBV Infection in HBsAg Positive Blood Circulation
by: Lin Wei, et al.
Published: (2021-08-01)

Assessment of hepatic fibrosis and necroinflammation among inactive HBsAg carriers in Egypt
by: Amr Abdelkader Fateen, et al.
Published: (2012-07-01)

Influence of HBV-DNA load on portal venous pressure and its molecular mechanism in HBsAg positive chronic HBV liver cirrhosis
by: Lang Xiao
Published: (2016-05-01)

Frequency of HBsAg in pregnant women in Gorgan, Iran
by: Cheraghali F (MD), et al.
Published: (2012-01-01)

Using dried blood spot for the detection of HBsAg and anti-HCV antibodies in Cameroon
by: Sebastien Kenmoe, et al.
Published: (2018-11-01)

Protracted HBsAg-aemia in a Patient with Acute Hepatitis B
by: K. R. Dudina, et al.
Published: (2018-11-01)

Association between HBsAg clearance and serum level of granulocyte-macrophage colony stimulating factor in inactive HBsAg carriers receiving pegylated interferon alpha-2a
by: CAO Zhenhuan, et al.
Published: (2018-05-01)

Incidência pós-transfusional do HBsAg em crianças com doenças neoplásicas Post-transfusional incidence of HBsAg in children with neoplastic diseases
by: Maria Zélia Fernandes, et al.
Published: (2009-04-01)

Course of a HBsAg positive liver transplantation in a hepatitis B and D virus coinfected recipient
by: Ralf Bahde, et al.
Published: (2011-07-01)

Frequency of HbsAg and Anti-HCV among Hemodialysis Patients in three Genral Hospitals of Azad Jammu and Kashmir State
Published: (2020-01-01)

Türk ve Mülteci Gebelerde HBsAg, Anti-HBs, Anti-HCV ve Anti-HIV Seropozitifliklerinin Karşılaştırılması
by: Şerife Yılmaz, et al.
Published: (2021-01-01)

Detection of HBV-DNA by Two PCR Methods in HBsAg Positive Sera, and Comparison of the Results with Serological Markers
by: Emine SÖNMEZ, et al.
Published: (1996-09-01)

Increased Coffee Intake Reduces Circulating HBV DNA and HBsAg Levels in HBeAg-Negative Infection: A Cohort Study
by: Jack Bee Chook, et al.
Published: (2019-09-01)

Seroprevalence of HBsAg, Anti-HBs, Anti-HCV and Anti-HIV in Behçet’s Disease
by: Esma Eroğlu, et al.
Published: (2021-05-01)

Seroprevalence of HbsAg, anti-HBc and anti-HCV in Southern Brazil, 1999-2001
by: Nilton Rosini, et al.

Seroprevalence of HbsAg, anti-HBc and anti-HCV in Southern Brazil, 1999-2001
by: Rosini Nilton, et al.
Published: (2003-01-01)

Clinical implications of HBsAg quantification in patients with chronic hepatitis B
by: Mauro Viganò, et al.
Published: (2012-01-01)

Cloning of HBsAg Gene of Hepatitis B Virus in to an Expression Vector
by: Aykut ÖZDARENDELİ, et al.
Published: (2003-09-01)

Quantitative HBsAg levels do not identify hepatic fibrosis in HBeAg-negative chronic hepatitis B patients
by: Fatima A Ahmed, et al.
Published: (2019-01-01)

Prevalence of hepatitis D virus among HBsAg-positive individuals,2015-2016: Azar cohort study
by: Ali Asghar Pouri, et al.
Published: (2020-01-01)

Evaluation of Chronic Hepatitis B Infection in Patients With Seronegative HbsAg
by: N Sadeghifard, et al.
Published: (2012-02-01)

Evaluation of Chronic Hepatitis B Infection in Patients with Seronegative HbsAg
by: E Gholami Parizad, et al.
Published: (2012-02-01)

Mitogen-activated protein kinase eight polymorphisms are associated with immune responsiveness to HBV vaccinations in infants of HBsAg(+)/HBeAg(−) mothers
by: Meng Zhuo Cao, et al.
Published: (2018-06-01)