Persisting alterations of iron homeostasis in COVID-19 are associated with non-resolving lung pathologies and poor patients’ performance: a prospective observational cohort study

Persisting alterations of iron homeostasis in COVID-19 are associated with non-resolving lung pathologies and poor patients’ performance: a prospective observational cohort study

Abstract Background Severe coronavirus disease 2019 (COVID-19) is frequently associated with hyperinflammation and hyperferritinemia. The latter is related to increased mortality in COVID-19. Still, it is not clear if iron dysmetabolism is mechanistically linked to COVID-19 pathobiology. Methods We...

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Bibliographic Details
Main Authors: Thomas Sonnweber, Anna Boehm, Sabina Sahanic, Alex Pizzini, Magdalena Aichner, Bettina Sonnweber, Katharina Kurz, Sabine Koppelstätter, David Haschka, Verena Petzer, Richard Hilbe, Markus Theurl, Daniela Lehner, Manfred Nairz, Bernhard Puchner, Anna Luger, Christoph Schwabl, Rosa Bellmann-Weiler, Ewald Wöll, Gerlig Widmann, Ivan Tancevski, Judith-Löffler-Ragg, Günter Weiss
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Respiratory Research
Subjects:
COVID-19
SARS-CoV-2
Iron metabolism
Hyperferritinemia
Hepcidin
Online Access:http://link.springer.com/article/10.1186/s12931-020-01546-2

Internet

http://link.springer.com/article/10.1186/s12931-020-01546-2

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