The matrix-dependent 3D spheroid model of the migration of non-small cell lung cancer: a step towards a rapid automated screening

The matrix-dependent 3D spheroid model of the migration of non-small cell lung cancer: a step towards a rapid automated screening

In vitro 3D cell culture systems utilizing multicellular tumor spheroids (MCTS) are widely used in translational oncology, including for studying cell migration and in personalized therapy. However, early stages of cellular migration from MCTS and cross-talk between spheroids are overlooked, which w...

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Bibliographic Details
Main Authors: Evgenya Y. Shabalina, Ekaterina Yu Skorova, D. A. Chudakova, V. B. Anikin, I. V. Reshetov, O. A. Mynbaev, E. V. Petersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
3D cell culture
multicellular tumor spheroids
non-small cell lung cancer
metastasis
microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.610407/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.610407/full

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