Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy

Abstract The constant increase in cardiovascular disease rate coupled with significant drawbacks of existing therapies emphasise the necessity to improve therapeutic strategies. Natural flavonoids exert innumerable pharmacological effects in humans. Here, we demonstrate the effects of chrysin, a nat...

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Bibliographic Details
Main Authors: Divyashree Ravishankar, Maryam Salamah, Alda Attina, Radhika Pothi, Thomas M. Vallance, Muhammad Javed, Harry F. Williams, Eman M. S. Alzahrani, Elena Kabova, Rajendran Vaiyapuri, Kenneth Shankland, Jonathan Gibbins, Katja Strohfeldt, Francesca Greco, Helen M. I. Osborn, Sakthivel Vaiyapuri
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05936-3