STAT6 Is Critical for the Induction of Regulatory T Cells In Vivo Controlling the Initial Steps of Colitis-Associated Cancer

STAT6 Is Critical for the Induction of Regulatory T Cells In Vivo Controlling the Initial Steps of Colitis-Associated Cancer

Inflammation is the main driver of the tumor initiation and progression in colitis-associated colorectal cancer (CAC). Recent findings have indicated that the signal transducer and activator of transcription 6 (STAT6) plays a fundamental role in the early stages of CAC, and STAT6 knockout (STAT6<...

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Bibliographic Details
Main Authors: Yael Delgado-Ramirez, Angel Ocaña-Soriano, Yadira Ledesma-Soto, Jonadab E. Olguín, Joselín Hernandez-Ruiz, Luis I. Terrazas, Sonia Leon-Cabrera
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
STAT6
colorectal cancer
regulatory T cells
colitis-associated-cancer
Online Access:https://www.mdpi.com/1422-0067/22/8/4049

Internet

https://www.mdpi.com/1422-0067/22/8/4049

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