Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22

Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22

Background. The coronary heart disease (CHD) risk locus on 21q22 (lead SNP rs9982601) lies within a “gene desert.” The aim of this study was to assess if this locus is associated with CHD risk factors and to identify the functional variant(s) and gene(s) involved. Methods. A phenome scan was perform...

Full description

Bibliographic Details
Main Authors: Katherine E. Beaney, Andrew J. P. Smith, Lasse Folkersen, Jutta Palmen, S. Goya Wannamethee, Barbara J. Jefferis, Peter Whincup, Tom R. Gaunt, Juan P. Casas, Yoav Ben-Shlomo, Jacqueline F. Price, Meena Kumari, Andrew Wong, Ken Ong, Rebecca Hardy, Diana Kuh, Nicholas Wareham, Mika Kivimaki, Per Eriksson, Steve E. Humphries, UCLEB Consortium
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2017/1096916

Internet

http://dx.doi.org/10.1155/2017/1096916

Similar Items