Oxoisoaporphine as Potent Telomerase Inhibitor

Two compounds previously isolated from traditional Chinese medicine, Menispermum dauricum (DC), 6-hydroxyl-oxoisoaporphine (H-La), and 4,6-di(2-pyridinyl)benzo[h]isoindolo[4,5,6-de]quinolin-8(5H)-one (H-Lb), were known to have in vitro antitumor activity and to selectively bind human telomeric, c-my...

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Bibliographic Details
Main Authors: Zu-Zhuang Wei, Qi-Pin Qin, Jia-Nian Chen, Zhen-Feng Chen
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/11/1534