Application of Response Surface Methodology for Optimisation of Simultaneous UHPLC-PDA Determination of Oleanolic and Ursolic Acids and Standardisation of Ericaceae Medicinal Plants

A fast and sensitive ultra-high performance liquid chromatography-photodiode array (UHPLC-PDA) method for simultaneous quantification of oleanolic acid (OA) and ursolic acid (UA) in plant materials was developed. A central composite design combined with a response surface methodology was utilized to...

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Bibliographic Details
Main Authors: Aleksandra Owczarek, Łukasz Kuźma, Halina Wysokińska, Monika Anna Olszewska
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Applied Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3417/6/9/244