GFAP Expression as an Indicator of Disease Severity in Mouse Models of Alexander Disease
AxD (Alexander disease) is a rare disorder caused by heterozygous mutations in GFAP (glial fibrillary acidic protein) resulting in accumulation of the GFAP protein and elevation of Gfap mRNA. To test whether GFAP itself can serve as a biomarker of disease status or progression, we investigated two i...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2013-02-01
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| Series: | ASN Neuro |
| Online Access: | https://doi.org/10.1042/AN20130003 |