Sox17-Mediated XEN Cell Conversion Identifies Dynamic Networks Controlling Cell-Fate Decisions in Embryo-Derived Stem Cells

Little is known about the gene regulatory networks (GRNs) distinguishing extraembryonic endoderm (ExEn) stem (XEN) cells from those that maintain the extensively characterized embryonic stem cell (ESC). An intriguing network candidate is Sox17, an essential transcription factor for XEN derivation an...

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Bibliographic Details
Main Authors: Angela C.H. McDonald, Steffen Biechele, Janet Rossant, William L. Stanford
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714008092